Sleep
Every sleep claim we've checked against the studies, newest first, each graded from Solid to Debunked by the evidence in people.

Magnesium Glycinate Does Help You Sleep, a Little
In the largest trial, 250 mg of magnesium glycinate at bedtime eased a poor-sleep score more than a dummy capsule. The gain was small, in one 4-week study.

Morning coffee drinkers: 29% fewer deaths at 2-3 cups
In 40,725 US adults, 2 to 3 cups before noon went with 29% fewer deaths over 10 years. In a trial, a daily cup cut heart-rhythm relapses by 39%.

One dose of creatine sharpened memory after a sleepless night
After 21 hours awake, one big dose of creatine raised word memory 10.3% and thinking speed up to 29% over placebo. Rested young adults gained little.

In deep sleep, fluid pulses through your brain every 20 seconds
Brain scans of sleeping adults show waves of fluid about every 20 seconds, timed to slow brain waves. Small human studies suggest sleep clears more waste.

Kids moved 45 more minutes a day when screens were put away
In a Danish trial of 181 children, two weeks of almost no leisure screen time added 46 active minutes a day and better behavior. No trial has run longer.

MK-677 (ibutamoren) kept growth hormone young for a year
In a year-long trial of 65 adults aged 60 to 81, MK-677 raised growth hormone 1.8-fold and added about 6 pounds, but strength did not change and blood sugar rose.

Pinealon restored brain-cell connections in mice bred to get Alzheimer's
Pinealon's best study is in mice: two months of shots restored 11% of lost nerve-cell connections. No study has measured its effect on sleep.

Six months of sermorelin left older adults sleeping and lifting the same
In the one placebo-controlled trial, 89 adults aged 60 to 85 took sermorelin for 6 months. Growth hormone doubled and thinking tests rose slightly; strength did not.

Does ipamorelin work? It raises growth hormone for a few hours
One dose of ipamorelin raised growth hormone in healthy men for under 6 hours. Its patient trials showed no clear benefit, and clinic shots have no published study.

