Growth hormone

Every growth hormone claim we've checked against the studies, newest first, each graded from Solid to Debunked by the evidence in people.

An unimpressed man of about 50 with his arms crossed, next to a small glass vial labeled AOD-9604 standing on a white bathroom scale
Oct 8, 2026 Grade: Debunked

AOD-9604 added under 1 kg of weight loss in a 502-person trial

502 adults took an AOD-9604 tablet or a placebo daily for 24 weeks and lost about the same weight. The injection sold today has never had a human trial.

A wincing man in his 30s in a gym, next to a white pill bottle labeled MK-677 on its side with capsules spilled in front of a dumbbell
Oct 7, 2026 Grade: Weak

MK-677 (ibutamoren) kept growth hormone young for a year

In a year-long trial of 65 adults aged 60 to 81, MK-677 raised growth hormone 1.8-fold and added about 6 pounds, but strength did not change and blood sugar rose.

A woman in her 60s next to a wooden hourglass and a glass vial labeled Sermorelin on a wooden table
Oct 5, 2026 Grade: Weak

Six months of sermorelin left older adults sleeping and lifting the same

In the one placebo-controlled trial, 89 adults aged 60 to 85 took sermorelin for 6 months. Growth hormone doubled and thinking tests rose slightly; strength did not.

A woman in her 50s at a kitchen table with an open shipping box, frowning at a small glass vial labeled Ipamorelin that she is holding up
Oct 5, 2026 Grade: Unproven

Does ipamorelin work? It raises growth hormone for a few hours

One dose of ipamorelin raised growth hormone in healthy men for under 6 hours. Its patient trials showed no clear benefit, and clinic shots have no published study.

A doubtful woman in her 30s next to a glass vial labeled CJC-1295 standing in front of a magnifying glass
Oct 5, 2026 Grade: Unproven

CJC-1295's only human evidence is a hormone blood test

One CJC-1295 shot raised growth hormone 2 to 10 times for a week in healthy adults. Its only patient trial stopped in 2006, and clinic versions are untested.

A man in his 30s looking toward a coiled yellow tape measure and a glass vial labeled Tesamorelin on a table
Oct 5, 2026 Grade: Promising

Tesamorelin for belly fat: deep fat fell about 15% in trials

In two trials of 806 people with HIV, daily tesamorelin cut the fat around the organs by about 15% in six months. The fat came back within six months of stopping.